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Paludrine and Avloclor

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What is Paludrine and Avlocor?

Paludrine and Aclovor is an anti-malaria treatment that has been clinically proven to minimise the risk of you getting malaria if bitten by an infected mosquito while travelling abroad to a low to high risk area.

This treatment is different to other anti-malarial treatments as it doesn't contain one medication but two that have to be taken in a different dose over a number of weeks. The combination of both treatments increases the recovery and likelihood to prevent the spread of the parasite. It also minimises the risk of sensitivity that some people experience when taking this type of medication.

What are the benefits?

The primary benefit of Paludrine/Avloclor tablets is that they offer effective, dual-action protection against a range of malaria parasites. It is particularly recommended in areas that are considered to be of lower risk like India. Paludrine/Avloclor tablets are particularly beneficial to people who are particularly sensitive to certain medications, because their mild dosage is less likely to cause side effects than other antimalarials.

How does Paludrine/Avloclor work?

The chloroquine phosphate in the Avloclor tablets attacks the malaria parasites after they have entered the red blood cells and stops them from multiplying. It does this by stopping a chemical that is produced by the parasites to protect them-selves. When this protection is gone, the parasites are vulnerable to the natural defence mechanisms of the body.

The proguanil hydrochloride in the Paludrine tablets also prevents the malaria parasites from multiplying, though in a slightly different way. It targets the enzyme responsible for the reproduction of the parasite. Without this ability, the parasite cannot spread.

Both of the ingredients work together to provide you with a preventative treatment for malaria to fight the infection before it is able to spread to the liver where it can cause damage to your internal organs. In doing so it lets the natural immune system fight the infection quickly without having to keep attacking it as it spreads. Unlike some antimalarial treatments Paludrine and Avloclor can also work on strains of malaria that are resistant to chloroquine alone.

How to take Paludrine/Avloclor tablets

Because of the different actions of the Paludrine and Avloclor medication and dosages the medication has to be taken according to the specific instructions to be effective. You should read the instructions before taking this medication to ensure you take them correctly. An outline of how the medication needs to be taken is outlined below:

  • Paludrine – two tablets every day at the same time
  • Avloclor – two tablets once weekly on the same day each week

Paludrine and Avloclor should be taken for at least a week before you leave on holiday and continued throughout your trip abroad. When you return home you should continue to take it for a further five weeks.

If you forget to take your dose you should take it as soon as you remember unless it is close to the time you are due to take your next dose. You should not double dose.

In addition to taking Paludrine and Avloclor you should also prevent getting bitten by:

  • Sleeping with a mosquito net for protection
  • Use insect spray
  • Wear long sleeves and long trousers leaving the least amount of skin exposed as possible.

Dosages

Paludrine and Avloclor antimalarial tablets are available online in a dose of 100mg/250mg in packs of 112 and 224.

Precautions when taking Paludrine/Avloclor tablets?

Paludrine/Avloclor tablets are considered safe for most people who are over 18. However, you should make sure you note any medical conditions you have or any medications you are taking during your online consultation. The medication may not be suitable for:

  • those taking antacids as they can reduce the absorption of the treatment
  • the elderly
  • those deficient in G6PD
  • those with liver or kidney problems
  • have a neurological problem
  • Have a gut or blood disorder

It is advised also not to take Paludrine and Avloclor if you are allergic to any of the ingredients.

What are the side effects of Paludrine/Avloclor?

The likelihood is that you will not experience any side effects while you take either the Avloclor tablets or the Paludrine tablets. However, this is a small possibility of some mild effects such as:

Common:
  • Headaches
  • stomach upsets
  • Mouth ulcers

The risk of these effects will be reduced if you only take the tablets after food.

When you fill in the online consultation form you should ensure you fill in all of the details so that the prescribing doctor can make sure the malaria treatment is right for you. If you show any signs of allergic reaction including rash, facial swelling or difficulty breathing you should seek medical advice immediately.

If you are concerned about any side effect you should contact a healthcare professional for advice. If you experience a severe reaction you should seek medical assistance immediately.

Can I buy the Paludrine/Avloclor Travel Pack online?

The Paludrine/Avloclor Travel Pack is available to buy online at euroClinix. To order this treatment, all you need to do is complete a free online consultation to determine your suitability for the medication. Once a doctor has assessed the consultation, you will be issued a prescription for the anti-malarial tablets, which will be dispensed from our pharmacy. With our free overnight delivery service, you can be sure that you will receive your medication quickly and securely.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Medically reviewed by Dr. Rebecca Littleford MBChB/MRCGP/DRCOG Written by our editorial team
Last reviewed 15-06-2022
Paludrine and Avloclor information
Product namePaludrine & Avloclor
Active ingredient(s)Chloroquine Phosphate and Proguanil Hydrochloride
ManufacturerAstraZeneca
Trustpilot rating4.7/5
Trustpilot reviews7
AvailabilityOut of stock
DescriptionThis treatment pack contains two types of anti-malarials used to prevent malaria when travelling abroad
ExemptionSubject to medical prescription
AdministrationOral
PresentationTablets
Available dosage100mg / 200mg
ApplicationMen and women over 18 travelling aboard
UsageStart taking 1 week before your trip and continue taking until 4 weeks after your return
Drug classAntimalarials
Alcohol consumptionCan cause side effects - take caution or avoid alcohol consumption, seek a GP for further advice
When breastfeedingNot recommended, ask your doctor for alternatives
When pregnantNot recommended, ask your doctor for alternatives
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Paludrine and Avloclor reviews
Excellent 4.7 7 patients have reviewed Paludrine and Avloclor on Trustpilot
31 Aug

Fast efficient service

graham taylor
08 Nov

Has really helped with my cholesterol levels.

Mrs C
01 Mar

Does what its supposed to do. Very pleased with this product.

Mrs C
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