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Please note that the first line treatment for cystitis that is caused by a bacterial UTI is Nitrofurantoin, as there is quite a high bacterial resistance to Trimethoprim. Therefore it is wise to only use Trimethoprim to treat a UTI after a urine test has confirmed that the bacterial strain causing the infection is sensitive to Trimethoprim. Please note that this treatment is currently only offered for female patients. If you are male and are experiencing symptoms of a urinary tract infection, you should visit your GP or a sexual health clinic as this could be a sign of another infection or a more serious underlying problem.


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What is Trimethoprim?

Trimethoprim is an antibiotic used to treat urinary tract infections (UTIs) such as cystitis. It also helps to reduce uncomfortable symptoms quickly. It is sold under several brand names, including Monotrim, Minotrim and Trimogal.

Whilst Trimethoprim is occasionally prescribed to treat other kinds of bacterial infections such as acne or chest infections, it is sold at euroClinix only for the treatment of UTIs.

You can buy the 200mg dose online at euroClinix. All you have to do is fill out a short and discreet consultation form and one of our registered doctors.

Please note: Trimethoprim is not the first-line treatment for cystitis. It can only be prescribed if a urine test has shown you have a UTI that is sensitive to Trimethoprim. Consult your GP if you are unsure.

How does Trimethoprim work?

Trimethoprim kills the bacteria that cause infections by preventing them from making certain enzymes. This stops the bacteria from spreading and kills the infection.

Trimethoprim was designed to tackle specific types of bacteria such as E.coli. These bacteria tend to be more difficult to kill and are more likely to become resistant to treatment. For that reason, you must take Trimethoprim exactly as prescribed.

How long does it take for Trimethoprim to work?

For most women, Trimethoprim should clear the infection in 3 days. However, some women may need longer. If your infection has not cleared after the treatment course, speak to your doctor.

For men, the infection should clear in 7 days.

Who can take Trimethoprim?

Trimethoprim is a commonly used antibiotic and is safe for most people. However, you should not take it if you:

  • are allergic to the ingredients
  • are pregnant or breastfeeding
  • have severe liver problems
  • have a blood disorder

Ask a doctor before taking if you have:

  • kidney problems, kidney disease or are having dialysis treatment
  • a folate deficiency (lack of folic acid)
  • a disorder called porphyria
  • intolerance to some sugars
  • high potassium levels in your blood

While men can take Trimethoprim, we cannot prescribe it to men online. This is because a UTI in men is often more serious.

Please read the patient information leaflet for more information on who can and cannot take it.

What dosage of Trimethoprim should I take?

The dose you need to take will depend on several factors.

To treat an acute UTI, women should take 200mg twice daily for 3 days. Men should take it twice daily for 7 days. Children will require a lower dose of 100mg.

If you struggle with frequent UTIs, you can take Trimethoprim to prevent symptoms:

  • take 100mg once daily before bed
  • take one 200mg tablet after exposure to a trigger

You must take the dosage as instructed for Trimethoprim to work.

How do I take Trimethoprim?

Trimethoprim tablets should be swallowed whole with a glass of water. You can take them with or without food.

You must take antibiotics exactly as instructed. Even if your symptoms improve quickly, you should always finish the entire course of antibiotics. It could cause your infection to return or become harder to treat.

If you miss a dose, take your missed dose when you remember and then your next dose at your usual time. If you miss a dose, and it’s nearly time for your next dose, skip the missed dose and continue from your next scheduled dose.

Always read the patient information leaflet before starting any new medication. You can find the patient information leaflet at the bottom of this page.

Can I drink alcohol whilst on Trimethoprim?

You can drink alcohol while on Trimethoprim. However, the effects of alcohol can cause some side effects whilst using this medication. So, it’s advised you drink in moderation.

Does Trimethoprim react with other medicines?

Trimethoprim can react with other medications, so you should check with your doctor before ordering any medication online.

Some interactions include with:

  • certain heart medications
  • medications for high blood pressure
  • diuretics
  • rifampicin - an antibiotic often used to treat tuberculosis
  • anticoagulants (e.g warfarin) - prevent blood clots
  • certain epilepsy treatments such as phenytoin
  • certain antiparasitics to treat malaria
  • dapsone - is used to treat skin conditions and leprosy
  • immunosuppressant drugs (e.g methotrexate or cyclosporine) - for cancer treatment or to prevent organ rejection after a transplant
  • bone marrow depressants

If you are unsure whether you take any of these medications, please consult your GP or a healthcare professional.

What are the side effects of Trimethoprim?

As with all medications, there is a chance you may experience some side effects.

Some of the most common side effects of Trimethoprim include:

  • feeling sick
  • diarrhoea
  • headache
  • itching or mild skin rash
  • thrush
  • hives

These side effects are usually mild and go away once you have finished treatment. However, if your symptoms don’t go away or you experience more severe side effects, consult your doctor as soon as possible.

Refer to the patient leaflet for a complete list of side effects.

How do I buy Trimethoprim online?

You can buy Trimethoprim tablets online from euroClinix. Our service is certified safe by the MHRA, GMC and GPhC.

All you have to do is complete an online consultation form. Then, one of our UK doctors will review your consultation to ensure that this treatment is suitable for you. If approved, your prescription will be dispatched and dispensed by our pharmacy. Your order will then be sent with free next-day delivery, so you can start to get better sooner.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Medically reviewed by Dr. Anand Abbot MRCGP Written by our editorial team Last reviewed 03-02-2024
Trimethoprim information
Product nameTrimethoprim
Active ingredient(s)Trimethoprim
Trustpilot rating4.7/5
Trustpilot reviews88
AvailabilityOut of stock
DescriptionAntibiotic used to treat and prevent cystitis.
ExemptionSubject to medical prescription
Available dosage200mg
ApplicationWomen with acute cystitis.
PosologyConsult patient leaflet
Drug classAntibiotics
Alcohol consumptionNo interaction
When breastfeedingCaution recommended, consult your doctor
Trimethoprim reviews
Excellent 4.7 88 patients have reviewed Trimethoprim on Trustpilot
23 Jan

Very good antibiotic always treats the symptoms quickly and completely

Customer Mrs Joyce Percival
09 Nov

First prescribed for my chronic cystitis years ago and still reliable today. Complaint managed by 1x100mg every third or fourth day and never any side...

Hazel Whinfrey
21 Mar

Very good product always produces excellent results

Customer Mrs Joyce Percival

Further reading

Cystitis causes: a comprehensive guide

Cystitis causes: a comprehensive guide

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Painful bladder syndrome: how to know when your cystitis could be chronic

Painful bladder syndrome: how to know when your cystitis ...

Reviewed by Dr. Plauto Filho
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