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Alleviate menopausal symptoms effectively with the Evorel patch

  • Pack of 8 Evorel 25 estradiol transdermal patches
  • Box of Evorel 25 with a sachet
  • Sachet of Evorel transdermal patch
  • Box of Evorel treatment with patient leaflet
4.8 114 patient review(s) review
Dr. Caroline Fontana Prescribing Doctor
(GMC Reg: 7526266)

What is Evorel?

Evorel patches contain the active ingredient estradiol. This active ingredient acts as a naturally occurring form of the central female sex hormone, oestrogen. The declining levels of oestrogen can cause distressing symptoms, such as irregular periods, hot fleshes, night sweats, mood swings and vaginal dryness or itching.

Oestrogen can be used as a supplement to replace the decreasing levels within the body and make the distressing symptoms caused by menopause more tolerable. This method is known as hormone replacement therapy. Your doctor should review the use of hormone replacement therapy at least once a year. This treatment is only required for a short-term relief.

Within the time scale that the menstrual cycle occurs, the oestrogen that the ovaries produce decreases. This results in a decline of oestrogen blood levels.

What are the benefits?

For those who do not like taking tablets daily, this medication provides an alternative method in the form of a patch, which you are required to change just twice a week. These patches supply heavy doses of oestrogen into the skin to increase oestrogen levels and help alleviate symptoms of the menopause including hot flushes, vaginal itching or dryness and irregular periods. Evorel is available in four different sizes Evorel 25, Evorel 50, Evorel 75 and Evorel 100, which correspond to the four different strengths.

Evorel 50, 75, 100 may also be used as a second-option treatment for osteoporosis in menopausal women.

How do Evorel patches work?

This medication contains the active ingredient estradiol, a form of the female hormone oestrogen. Leading up to the menopause can cause a woman’s ovaries to produce less oestrogen and low oestrogen blood levels, which can create a number of unpleasant symptoms to occur. Evorel patches replace the natural oestrogen and reduce menopausal symptoms by passing the estradiol hormone from the patch into the body via the skin. The supplement of active oestrogen into the body is reached approximately four hours after the patch is applied to the skin, lasting for three to four days, after which it should be changed.

Who cannot use Evorel patches?

Evorel patches are suitable for postmenopausal women aged between 40-60 (ideally up to their mid fifties) who have had a hysterectomy. If you have not had a hysterectomy and therefore still have a womb, it recommended that you also be prescribed a progestogen to take with this HRT to reduce the risk of cancer of the womb. High levels of oestrogen can stimulate the womb leading to the risk of endometrium cancer. If you are allergic to any of the ingredients, have a history of breast cancer, cancer of the womb, unexplained vaginal bleeding, blood clots, heart attacks, angina, liver dysfunction, porphyrias or are pregnant or breastfeeding, then this medication is not suitable for you.

How do you use Evorel?

Evorel patch is available in four different sizes. However, Evorel 50 is generally the starting prescribed dose for the treatment of menopausal symptoms. The patch should be applied to clean dry skin as soon as it is removed from the wrapper, with each application made on a slightly different area of the skin when changed. This medication should not be applied on or near the breasts.

It is important to take this medication as prescribed by your doctor. If the patch falls off it should be replaced as soon as possible. If the patch falls off while bathing or showering you must replace the patch once your skin has dried. If you forget to replace a patch it is recommended that you change it as soon as possible and keep to the original ‘patch change’ days.

What are the side effects with Evorel?

Like all medications there may be some side effects with this medication. Side effects include breakthrough bleeding, spotting, breast pain, tenderness and enlargement, headache, migraine, vaginal thrush, anxiety, depression, leg cramps, skin rash or itch, disturbances in liver function, irregular brown patches on skin, blood clots, weight changes, nausea, blotting, abdominal pain, ingestion, premenstrual symptoms and steepening of corneal curvature.

How can this medicine affect other medicines?

It's important to be open when discussing the medicines that you're using alongside Evorel whilst under-taking your online consultation, including those bought without a prescription and herbal medicines. Similarly, to ensure that the combination is safe, it is advised that you check with your doctor or pharmacist before taking any new medicines while using Evorel.

The following medicines potentially can reduce the optimum effectiveness of this medicine and also may reduce your blood levels. This could result in the reappearance of symptoms previously experienced or irregular bleeding:

  • Antiepileptic medicines such as carbamazepine, phenytoin, phenobarbital and primidone
  • Barbiturates such as amobarbital
  • Protease inhibitors for HIV infection such as ritonavir and nelfinavir
  • Rifamycin antibiotics such as rifabutin and rifampicin
  • The herbal remedy St John's wort (Hypericum perforatum).

How can I buy this medicine?

Evorel patches are available to buy at euroClinix. As this treatment is a prescription medication, you will be required to complete a simple online consultation form, where a qualified doctor will asses whether this medication is suitable for you. If approved for this medication, our doctor will issue a prescription for this treatment, which will be sent to our registered pharmacy for dispatch.

Treatment Information
Treatment Information
Product Name: Evorel
Active Ingredient(s): Estradiol
Manufacturer: Janssen Cilag
Description: Evorel is a hormone replacement treatment working to replenish hormone levels and provide relief from menopausal symptoms
Exemption: Subject to medical prescription
Administration: Topical
Presentation: Patches
Available Dosage: 25mcg, 50mcg,75mcg, 100mcg
Application: Women over 18 looking to relieve the symptoms of menopause
Posology: Apply 1 patch below waist and change 2 times a week
Drug class: HRT, unopposed oestrogens
Alcohol consumption: No influence
When breastfeeding: Not applicable
When pregnant: Caution is recommended, ask your doctor and read the leaflet thoroughly for each treatment
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Service ratings
TXT_RATING_ALT_TEXT Excellent 4.8 7,545 patients have rated our service
Product ratings
Excellent 4.8 114 patients have reviewed Evorel
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Current reviews for the treatment Evorel

Rated with 4.8 based on 114 independent customer reviews (See all euroClinix reviews).

  • Excellent Product Review:: A safe and discreet hrt 17 Sep
  • Excellent Product Review:: the patch is very useful easy to use. very helpful to some hrt problems 08 Jul
  • Excellent Product Review:: It really works for me. It has cut down on all my night problems, hot flush, hea... 06 May
  • Excellent Product Review:: Excellent, first rate service. The staff are always very courteous and helpful w... 14 Dec
  • Excellent Product Review:: Very effective . No side effects 14 Dec