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  • Onglyza 5mg saxagliptin film-coated tablets
  • Box of Onglyza oral tablets with blister strips
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What is Onglyza?

Onglyza is a diabetes treatment that is taken orally. This prescription medicine works by controlling and regulating the levels of insulin your body produces after eating.

Onglyza has been clinically proven to keep blood sugar levels under control. For best results this treatment should be combined with a healthy diabetic diet and exercise. It may be prescribed on its own or used in conjunction with insulin and other Type 2 diabetes treatment options.

Onglyza is used to aid people with Type 2 diabetes. It can be used in combination with other diabetes medication, but not for Type 1 diabetes.

What are the benefits of this medication?

Type 2 diabetes results from the pancreas’ inability to produce enough insulin that is then inadequately used by the body. This results in blood sugar levels becoming dangerously high. Onglyza helps to control blood sugar levels effectively. It is a recommended treatment if diet, exercise and other oral diabetic medications have failed to control glucose levels. This medication can also be used in combination with insulin and certain other diabetes medications.

You can order this diabetes medication online from euroClinix after completing an online consultation. If approved, your prescription will then be passed on to our registered pharmacy, and the treatment will be sent out free of charge for delivery the next day.

How does Onglyza work?

Onglyza contains the active ingredient saxagliptin, which works by increasing the two hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP). Normally produced by the body as a result of food ingested, they work to control glucose levels. They do this by helping the pancreas produce more insulin and reducing the production of the hormone that increases glucose (glucagon), all of which controls sugar blood levels effectively. It is usually prescribed to complement other treatments that are not effective on their own, but is also prescribed on its own.

Who can take it?

Onglyza is suitable for people with Type 2 diabetes who have not experienced an improvement in the control of their blood sugar levels after dietary changes, increased exercise and other medication. This medication is not suitable if you are allergic to saxagliptin or any other ingredients in this medication. If you have Type 1 diabetes, diabetic ketoacidosis, kidney or liver problems, severe and persistent abdomen pain or acute pancreatitis then Onglyza will not be prescribed. Certain other medications, including other diabetes medications, should not be taken with Onglyza. This medication is not suitable for women who are pregnant or breastfeeding.

How do you take this medication?

The recommended dose for Onglyza is 5mg, which should be taken once daily, preferably with glass of water and at the same time everyday. If you have kidney problems or other health ailments, your doctor may reduce your dose to 2.5mg.

If you forget to take a tablet then take the missed tablet straightaway, unless it is near to the time for your next dose, in which case you should skip the missed dose. You should never take a double dose while taking this medication. Speak to a doctor if this occurs.

Before you take Onglyza you should read the enclosed instructions, or download them from the bottom of this page.

The active ingredient

Saxagliptin is the active ingredient in Onglyza. Saxagliptin belongs to a category of medicines called a dipeptidyl peptidase-4 inhibitor. This category of medicine is used to treat type 2 or non-insulin dependent diabetes.

The role of saxagliptin is to increase the quantity of two-incretin hormones located in the body called glucagon-like peptides-1 and glucose-dependent insulinotropic peptide. The production of these hormones within the body is normally natural, in response to food in-take. Their purpose is to help regulate and control blood sugar levels.

GLP-1 and GIP controls glucose in two different ways.

The pancreas is stimulated by GLP-1 and GIP, to react to rising levels of glucose in the blood.

The production of glucagon is also lowered by GLP-1.

An enzyme in the body called dipeptidyl peptidase-4 breaks down GLP-1 and GIP. The role of saxagliptin is to bind with this enzyme and prevent it from breaking down GLP-1 and GIP. The effectiveness when regulating levels of blood sugar rise by this process increasing the levels of these hormones in the body.

What are the side effects?

This medication may cause side effects although not everybody who takes it will experience them. Common side effects include vomiting, headache, dizziness and fatigue. Less common side effects include rashes, hypersensitivity reactions and pancreatitis. If you experience any side effects that concern you then you should speak to your doctor immediately.

Some precautions associated with Onglyza should be taken into account before buying this medication. You may either be offered a lower dose or an alternative option. These include if you're allergic to the ingredients, if you have kidney or liver conditions, acute pancreatitis, persistent severe abdominal pain or diabetic ketoacidosis. If you are pregnant or breastfeeding, or have Type 1 diabetes, you will not be offered Onglyza.

How do I buy this medication?

Onglyza is available to buy safely online at euroClinix once you have completed a fre and fast online consultation, which is completely free of charge. You will need to have been prescribed or recommended Onglyza previously by a doctor in order to buy it online, and once approved, your preferred treatment will be sent to your address of choice. After the form is completed, one of our licensed doctors will assess if the medication is appropriate and safe for you. A prescription will be sent to our pharmacy and your medication will be delivered to you next day for the UK on orders made before 4.30pm.

This medication should be taken without a break to continuously control high blood sugar levels. To ensure you do not run out of medication euroClinix offers a free prescription reminder service. You can also take advantage of the repeat prescription service that will allow you to place your orders even faster in future.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Onglyza information
Product nameOnglyza
Active ingredient(s)Saxagliptin
ManufacturerBristol Myers Squibb/AstraZeneca
Trustpilot rating-
Trustpilot reviews-
AvailabilityOut of stock
DescriptionOnglyza is a type 2 diabetes treatment that regulates blood sugar levels in those with type 2 diabetes
ExemptionSubject to medical prescription
Available dosage2.5mg
ApplicationMen and women over 18 with type 2 diabetes
UsageTake 1 tablet daily
Drug classDipeptidyl peptidase 4 inhibitor
Alcohol consumptionNo influence
When breastfeedingNot recommended, ask your doctor for alternatives
When pregnantNot recommended, ask your doctor for alternatives

Further reading

Understanding and managing Metformin's side effects

Understanding and managing Metformin's side effects

Reviewed by Dr. Caroline Fontana
What causes diabetes?

What causes diabetes?

Reviewed by Dr. Caroline Fontana
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