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What is Fluconazole?

Fluconazole is an antifungal medicine that can be used to treat a variety of fungal infections. It is commonly used to treat:

  • thrush occurring in both men and women
  • fungal balanitis (skin inflammation on the head of the penis)
  • fungal skin infections like athlete’s foot
An infographic displaying facts about Fluconazole, a treatment for thrush

It can also be used to prevent fungal infections in people with a compromised immune system and treat rare infections of the lungs and brain caused by a fungus called Cryptococcus.

How does it work?

Fluconazole is from a group of antifungal medicines known as triazoles. It works to treat infections by slowing down the growth of the fungus that’s causing problems.

For the majority of people who take Fluconazole, this fungus is known as Candida. It is a common fungus that’s responsible for causing genital and oral thrush.

To kill the fungus, Fluconazole attacks the cell membranes and causes the contents to leak out. By slowing down the growth of the fungus, your body can then fight off the infection and recover from any damage caused.

What are the benefits?

Fluconazole is easy to take and treats thrush both quickly and effectively.

To treat thrush, you only need to take one singular dose. This is beneficial because:

  • you don’t have to remember to take more capsules throughout the day
  • you’re less likely to experience side effects
  • your gut microbiome is less likely to be affected

You are likely to feel your symptoms improving within 24 hours of taking your Fluconazole treatment.

Who can take Fluconazole?

Fluconazole is safe for most people who require treatment for thrush. However, you should not take this medication if:

  • you have liver or kidney problems
  • you suffer from heart problems including heart rhythm problems
  • you have unusual levels of magnesium, potassium or calcium in your blood
  • you or your partner have been exposed to a sexually transmitted infection

You should also avoid this medication if you are currently taking:

  • astemizole and terfenadine - antihistamines for treating allergies
  • cisapride - for treating stomach upsets
  • pimozide - antipsychotic medicine
  • quinidine - for treating heart arrhythmia
  • erythromycin - an antibiotic used for treating infections

Pregnancy and breastfeeding

This thrush treatment should be avoided during pregnancy as Fluconazole can cause birth complications. Traces of Fluconazole can be found in breast milk which could also pose a risk for newborns.

It is always advised that pregnant women or new mothers seek medical advice before taking any kind of medicine.

How do I take Fluconazole?

Always take prescription medicines as per your doctor’s instructions. However, a guide on taking Fluconazole for the treatment of thrush is written below.

  • you can take Fluconazole with or without a meal
  • the usual recommended dose is one 150 mg capsule
  • swallow the capsule whole with a glass of water. Do not break or chew the capsule

Contact your doctor if your symptoms have not improved within one week.

What are the potential side effects?

Just like any kind of medicine, there’s a chance you’ll experience side effects from taking Fluconazole. While it’s common to get side effects, not everybody will experience them.

Common side effects (affecting 1 in 10 people) of Fluconazole include:

Common side effects:
  • headache
  • stomach ache or pain
  • diarrhoea
  • a skin rash
  • nausea (feeling sick)
  • vomiting (being sick)
  • increased liver function (shown in blood tests)

Uncommon side effects (affecting 1 in 100 people) include:

Uncommon side effects:
  • pale skin and weakness (due to a decrease in red blood cells)
  • decreased appetite
  • difficulty sleeping
  • constipation or difficulty digesting
  • muscle pain
  • yellowing of the eyes and skin (jaundice)

Please seek medical attention immediately if you experience any of the following symptoms:

An infographic displaying signs of a severe allergic reaction
  • a widespread rash, accompanied by a high fever and swollen lymph nodes
  • wheeziness, difficulty breathing, tightness in the chest, swelling of the eyelids, face or lips (these are signs of a serious allergic reaction)

Does Fluconazole react with any other medicines?

The following table contains a list of medicines that can interact with Fluconazole:

Medicines that can interact with Fluconazole
  • amiodarone (for heart arrhythmia)
  • fentanyl (anaesthetic)
  • methadone (for pain)
  • prednisone (steroid)
  • voriconazole and amphotericin B (antifungals)
  • medications for high blood pressure like losartan
  • theophylline (for asthma)
  • medications to prevent organ rejection after transplant like sirolimus or tacrolimus
  • oral contraceptives
  • zidovudine and saquinavir (for HIV)
  • benzodiazepines like midazolam
  • blood-thinning medications like warfarin
  • diabetic medications like glipizide
  • non-steroidal anti-inflammatory drugs (NSAIDs) like celecoxib
  • carbamazepine and phenytoin (anti-seizure medications)

Please note: For a full list of medications that can interact with Fluconazole, please refer to the patient information leaflet.

It’s important to tell your doctor about any other medications you are taking during your consultation. That way, they can only prescribe Fluconazole if it is safe to do so.

Can I buy Fluconazole online?

Yes, it’s possible to buy Fluconazole capsules online here at euroClinix. Please note that they can only be prescribed for the treatment of thrush.

Simply complete your consultation by filling out our online questionnaire. Your answers will then be reviewed by one of our registered doctors, who will offer you a prescription for Fluconazole if you are suitable for this treatment.

Once approved, your treatment will be sent out to you in discreet packaging with free delivery.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Medically reviewed by Dr. Caroline Fontana Written by our editorial team Last reviewed 17-04-2024
Fluconazole information
Product nameFluconazole
Active ingredient(s)Fluconazole
Trustpilot rating4.6/5
Trustpilot reviews19
AvailabilityOut of stock
DescriptionAntifungal medicine that effectively treats thrush
ExemptionSubject to medical prescription
Available dosage150 mg capsules
ApplicationMen and women over 18 with thrush
UsageFluconazole should be taken as per your doctor’s instructions
Drug classAnti-fungal
Alcohol consumptionNo known interaction
When pregnant/breastfeedingNot recommended
Fluconazole reviews
Excellent 4.6 19 patients have reviewed Fluconazole on Trustpilot

Further reading

Thrush during pregnancy

Thrush during pregnancy

Reviewed by Dr. Plauto Filho
Recurring thrush: causes and treatment

Recurring thrush: causes and treatment

Reviewed by Dr. Plauto Filho
How does thrush affect men and women differently?

How does thrush affect men and women differently?

Reviewed by Dr. Plauto Filho
Male thrush: the symptoms to look out for

Male thrush: the symptoms to look out for

Reviewed by Dr. Plauto Filho
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