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Home / Weight Loss / Mysimba

Mysimba

  • Mysimba
4 4 patient review(s) review
Content reviewed on 28-10-20 Dr. Anand Abbot Independent Medical Advisor
(GMC Reg: 4307024)

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

What is Mysimba?

Mysimba is a prescription weight-loss treatment. Each tablet contains 8 milligrams of naltrexone hydrochloride and 90 milligrams of bupropion hydrochloride.

It is available for those over the age of 18 who have a body mass index (BMI) of 30 or more. Alternatively, if you have a BMI of 27 to 30 and suffer from weight-related ailments, like high cholesterol or diabetes, you can be prescribed Mysimba.

Please note, this medication should be taken with a reduced-calorie diet and regular exercise regime.

How does it work?

The active ingredients of Mysimba (bupropion and naltrexone) work by altering the way the brain interprets hunger. Their combined effect reduces hunger pains and food cravings, helping you to stick with a low-calorie diet for longer.

If you are unsure if your diet is healthy, and do not know what exercise is appropriate for you to do, please speak with a doctor or health professional - they will be able to advise what is best.

It is also important to note, not all weight gain is a result of increased appetite. Psychological factors, such as anxiety and stress, can also play a part. For this reason, you should consult with your doctor before starting this medication - to determine the cause of your obesity.

How do I take it?

Full instructions of how to take this medication will be detailed in the patient information leaflet. This will be sent with your order and is also available to view on the right of this page.

If you are unsure about any instructions, please consult your doctor.

Mysimba is relatively easy to take and requires you to increase the dose slowly over the course of four weeks:

  • Week 1: take one tablet once a day in the morning
  • Week 2: take two tablets every day, one in the morning and one in the evening
  • Week 3: take three tablets every day, two in the morning and one in the evening
  • Week 4 and onward: take four tablets every day, two in the morning and two in the evening

You should stop taking Mysimba if you have not lost at least 5% of your initial body weight after 16 weeks of treatment. If you have lost 5% or more, the medication is working effectively and you can continue.

You should only stop taking Mysimba once you have spoken to your doctor.

After 16 weeks, you should have your progress monitored by your doctor. Make sure to visit them at least once annually.

If you forget to take a dose, skip it and continue as normal. Do not take a double-dose to make up for a missed tablet.

If you take too many tablets at once, you may be at risk of experiencing seizures. In this scenario, please seek immediate medical attention.

If you suffer from any liver or kidney conditions, please consult your doctor before starting this medication - they may advise a lowered dosage.

What are the possible side effects?

Mysimba is a prescription medication and all prescription medications pose a risk of side effects.

For a comprehensive list of side effects, please consult the patient leaflet. The most commonly occurring reactions include:

  • nausea
  • vomiting
  • constipation
  • dizziness
  • dry mouth
  • abdominal pain
  • headache
  • insomnia (reduce by avoiding dose at bedtime)

There have been reports of depression in those taking this medication. If you experience any anxiety, depression or suicidal thoughts, please seek immediate medical attention. Do not take these feelings lightly.

Mysimba also increases the risk of fits and loss of consciousness. This is a very rare side effect, but if you experience fits, seek immediate medical attention.

If you believe you are experiencing an allergic reaction to this treatment, you should discontinue treatment and seek immediate medical attention.

What precautions should I take?

There are a number of conditions that preclude the use of Mysimba. If you are unsure if any of the following apply to you, please contact your doctor for clarification.

You should not use Mysimba if you have:

  • liver or kidney issues
  • uncontrolled high blood pressure
  • history of psychological issues
  • a brain tumour
  • alcohol dependency
  • any drug dependency
  • are taking any opiates
  • history of seizures
  • history of head trauma

For further advice on what conditions preclude you from using Mysimba, please consult the patient leaflet.

Excessive alcohol use can increase the likelihood of fits with this medication. If you drink heavily, consult your doctor before starting this treatment. You should gradually reduce how much you drink if you are taking Mysimba. Stopping suddenly can also increase the risk of fits.

If you are pregnant, breastfeeding or trying to conceive, do not take this medication.

You should be cautious if you are aged over 65, and you should not take Mysimba if you are over 75 years of age.

Mysimba can cause dizziness when patients first start treatment. It has also been known to cause seizures. For this reason, you should first consider how you react before driving or operating machinery.

Can I buy Mysimba online?

Yes, you can buy Mysimba online. However, as a prescription medication, it is subject to strict prescribing guidelines. We require you to complete a consultation before you place your order. This is included in the overall price and is a way for our doctors to confirm the medication is safe to use.

The entire process, from order to delivery, should take no longer than 48 hours.

Treatment Information
Treatment Information
Product Name: Mysimba
Active Ingredient(s): Naltrexone/bupropion
Manufacturer: Orexigen Therapeutics
Description: Mysimba is an effective weight loss treatment
Exemption: Subject to medical prescription
Administration: Oral
Presentation: Tablets
Available Dosage: Prolonged-release tablets, 8 mg naltrexone and 90 mg bupropion
Application: Adults who are obese (have a body-mass index of 30 or above) or who are overweight (have a BMI of 27 or above) and have certain weight-related health complications
Posology:Consult patient leaflet
Drug class: Serotonin and noradrenaline reuptake inhibitors/opioid receptor antagonists
Alcohol consumption: Avoid alcohol consumption
When breastfeeding: Not recommended, ask your doctor for alternatives
When pregnant: Not recommended, ask your doctor for alternatives
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