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What is Spedra?

Spedra is one of the most recent medications to enter the market of erectile dysfunction treatments. It contains the active ingredient avanafil which helps you achieve and maintain an erection.

It is a clinically-proven and effective ED treatment, working as quickly as 30 minutes and effects can last for up to 5 hours.

Learn more about Spedra and order it online at euroClinix.

How does Spedra work?

Spedra is an ED medication that contains the active ingredient avanafil. Avanafil belongs to a group of medicines called PDE-5 inhibitors (phosphodiesterase type 5 inhibitors) alongside Sildenafil (Viagra), Tadalafil (Cialis) and Vardenafil (Levitra).

These medicines work by blocking the action of the enzyme PDE-5, which breaks down certain molecules produced during sexual stimulation. By doing so, this keeps the penile tissues relaxed and allows more blood flow through the blood vessels of the penis. This allows you to more easily get and sustain an erection.

It’s important to note that Spedra, as with other PDE-5 inhibitors, will only work if you are already sexually aroused.

How long does it take Spedra to work?

Spedra is very fast-acting, and will work after 30 minutes. The effects of Spedra will last for 4 - 5 hours. However, this will not mean you will have an erection for the entirety of that length of time.

Who can take Spedra tablets?

Spedra is only suitable for men over the age of 18, it cannot be prescribed to women for sexual dysfunction.

It also may not be suitable for some men with certain medical conditions and you should make sure you tell your prescriber your medical history so they can ensure it’s safe for you to take.

You should not take Spedra if you have:

  • a cardiac problem
  • angina (chest pain)
  • a condition that causes arrhythmia (irregular heartbeat)
  • had a heart attack or stroke
  • liver problems
  • kidney problems
  • uncontrolled low blood pressure or high blood pressure
  • non-arteritic ischemic optic neuropathy (NAION) - loss of vision caused by reduced blood supply to the eye
  • a family history of eye or cardiac problems

You should also not take Spedra if you have previously had an adverse or allergic reaction to Avanafil.

If you’re not sure if any of these categories apply to you, please consult your doctor before taking Spedra. For a full list of contraindications, please refer to the patient information leaflet which is available to download at the top of this page.

Which dosage of Spedra should I take?

There are three doses of Spedra available: 50, 100 and 200mg tablets.

  • Spedra 50mg - the lowest dose, suitable if you are prone to side effects of Spedra or you have taken the medium dose and found the effects too strong
  • Spedra 100mg - the initial recommended dose
  • Spedra 200mg - the highest dose, suitable if you find the the middle dose does not work

If it’s your first time taking Spedra, you should start by taking the 100mg dose. You can see how you react to it and then alter your dose depending on whether you need a stronger or lower dose.

How do I take Spedra tablets?

You should take Spedra tablet at least 30 minutes before sexual activity.

You can take Spedra with or without food on an empty stomach, but avoid eating a heavy meal before taking it. This can make the medicine take longer to work.

You should also avoid drinking alcohol or grapefruit juice with Spedra as this can increase the effects of the medicine and make you more at risk of experiencing side effects.

You should also wait to drive or operate machinery until you know how Spedra affects you, as Spedra can make you feel dizzy and affect your vision.

What are the possible side effects of Spedra?

As is the case with all prescription medicines, Spedra can cause some side effects. Thankfully, most common side effects are mild and will go away on their own.

Some common side effects of Spedra include:

  • headache
  • flushing
  • nasal congestion
  • dizziness
  • blurred vision
  • back pain
  • heart palpitations
  • indigestion
  • nausea
  • tiredness

If you experience any of the following side effects, stop taking Spedra and seek immediate medical attention:

  • have an erection lasting longer than 4 hours (priapism)
  • sudden loss of vision in one or both eyes
  • sudden reduction or loss of hearing

For a full list of side effects, please refer to the patient information leaflet.

Does Spedra interact with other medicines?

It’s important to inform your prescriber of all the medicines you are taking, including over-the-counter, prescription and recreational drugs to ensure Spedra is safe for you to take.

You should not take Spedra if you take any of the following:

  • nitrate medicines (e.g amyl nitrite or “poppers”)
  • HIV medicines
  • certain antifungal medicines (e.g ketoconazole or fluconazole)
  • certain antibiotic medicines (e.g clarithromycin or erythromycin)
  • other erectile dysfunction medicines

If you are taking any of the following, please consult your doctor before taking Spedra:

  • alpha-blockers - for prostate problems or high blood pressure
  • medicines for an irregular heartbeat (e.g quinidine)
  • medicines for epilepsy (e.g phenobarbital or primidone)
  • carbamazepine - for epilepsy or as a mood stabiliser

If you’re not sure what medicines you take or don’t know whether any of the above apply to you, please consult your doctor or pharmacist before taking Spedra.

How do I buy Spedra online?

Spedra dosages 50, 100 and 200mg are available at euroClinix for the treatment of erectile dysfunction. All you have to do is complete an online consultation that will be reviewed by one of our UK registered doctors. Once approved for treatment, our online pharmacy will dispatch and dispense your medicine with free next day delivery.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Medically reviewed by Dr. Mahesh Chhaya MBBS Written by our editorial team
Last reviewed 24-02-2023
Spedra information
Product name Spedra
Active ingredient(s) Avanafil
Manufacturer Menarini
Trustpilot rating 4.1/5
Trustpilot reviews 65
Availability Out of stock
Description A fast-acting erectile dysfunction treatment
Exemption Subject to medical prescription
Administration Oral
Presentation Tablets
Available dosage 50mg, 100mg and 200mg
Application Men over 18 with erectile dysfunction
Posology Consult patient leaflet
Drug class PDE-5 inhibitors
Alcohol consumption Not recommended
When pregnant/breastfeeding Not applicable
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Spedra reviews
Box of 4 Spedra® 200mg Avanafil oral tablets Excellent 4.1 65 patients have reviewed Spedra on Trustpilot
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