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Amlodipine Side Effects

Amlodipine is a commonly used medication used to treat high blood pressure in people who are at risk of developing serious complications because of the condition. It's known as a calcium channel blocker and is generally recommended to be used daily, which is why it is important that it doesn't cause you significant discomfort. Luckily, side effects with this medication are rare and many people are able to use it long term to help bring their blood pressure under control.


Tiredness and dizziness are quite commonly reported by those taking Amlodipine. It is far more rare to experience effects such as confusion, anxiety or changes in mood.


Nausea and indigestion are common side effects of Amlodipine. Vomiting is less common.


Flushing is a common side effect of this medication. The skin may become itchy or discoloured, though this is rarer.

Eyes and nose

Facial side effects are less common, but can include dry mouth, blurred vision, a runny nose and swollen gums.

Amlodipine side effects

Click on the relevant area of the body to find out about how it may be affected by Amlodipine

Common Amlodipine side effects

The most common side effects caused by Amlodipine are mostly avoidable and very mild in nature. They usually affect one to 10 in every 100 patients.

Uncommon Amlodipine side effects

One to ten in every 1,000 patients taking Amlodipine will experience uncommon side effects. If they worsen or persist for a long period of time you should consult a doctor

Rare Amlodipine side effects

These Amlodipine side effects only appear in fewer than one in every 1000 people. This includes allergic reactions which can cause swelling and difficulty breathing. If you experience an allergic reaction you should stop taking the medication and go to a hospital immediately.

Hot flushing
Weight change
Blurred vision
Dry mouth
Runny nose
Increased heart rhythm
Swollen gums
Mood changes

How to avoid Amlodipine side effects

One of the main reasons Amlodipine could lead to side effects is because it is not the most appropriate treatment for your condition. This could be because you are taking other medications or you may have a condition that could influence or could be influenced by how this medication functions.

This is why this is important that you mention any health problems or other medications you are taking when you speak to your doctor about this treatment.

It's particularly important not to take Amlodipine if you are allergic to the active ingredient, if you are in shock as a result of heart problems, have a narrowing of the heart valves or have low blood pressure.

You may also be more likely to develop Amlodipine side effects if you have liver problems, have poor heart function as a result of heart failure, if you are under the age of 18 or over 55. In these cases a doctor may choose to monitor your use of this medication more closely.

Medications that could increase the risk of Amlodipine side effects

Taking the following medications with Amlodipine may increase the risk of Amlodipine side effects or could inhibit the efficacy of the treatment:

  • Other medications used to treat high blood pressure such as ACE inhibitors
  • Ritonavir (antiviral medication)
  • Rifampicin (antibiotic drug)
  • St John's Wort
  • Diltiazem (for the treatment of heart disease)

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